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Center for Tissue Regeneration and Engineering at Dayton


The University of Dayton's Center for Tissue Regeneration & Engineering at Dayton (TREND) has been recognized as the Ohio's Centers of excellence in Biomedicine and Health care category. The TREND center has been established with the aim to generate collaborations across disciplines from Natural sciences to Engineering to understand the basic biology of how damaged tissues and organs can regenerate. Tissue engineering studies are directed to understand and develop regimen for regeneration of body tissue/organs to substitute for biological function of organs damaged by injury. Given the ability of cells in the body to participate in repair, it is imperative to understand how to harness such a property at will. In this respect, translating these basic concepts to engineer tissues might solve problems associated with poor regeneration and artificial tissues. This rapidly emerging field requires strength from various disciplines of modern day science including Genetics, Cell biology, Physiology, Neuroscience, Engineering, Biochemistry, Biophysics, Chemistry and Mathematics.


The TREND center was developed in 2004 with an idea to bring biomedical researchers, engineers and clinicians to bring their repertoire of tools to discern the molecular genetic basis of regeneration. The TREND center, the brain child of a highly accomplished and regenerative biologist Dr. Panagiotis Tsonis, was recognized the Center for Research Excellence by the state of Ohio. Dr. Tsonis employed highly versatile newt model to understand the molecular-genetic underpinnings of complex process of regeneration of lens and limbs. Dr. Tsonis passed away on September 3rd, 2016. Dr. Amit Singh took over as the interim Director of the TREND center on May 1st, 2017.

Finding new targets of amyloid plaque mediated neurodegeneration using Drosophila eye model, Amit Singh.


Biology Seminar: Anastasios A. Tsonis

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Early Eye Development

University of Dayton biologist Amit Singh is studying early eye development in fruit flies to understand the molecular basis of retinal disease and birth defects in the human eye under a new $439,499 grant from the National Institutes of Health.

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Center for Tissue Regeneration and Engineering at Dayton

300 College Park
Dayton, Ohio 45469