Anne R. Crecelius

Assistant Professor
Full-Time Faculty
School of Education and Health Sciences: Health and Sports Science

  • Location: College Park Center, Room 646B
  • Phone: 937-229-4373
  • Email: Contact

Courses Taught

  • HSS 307 Human Physiology
  • HSS 307L Human Physiology Lab
  • HSS 428 Research in Physical Activity and Health 

Degrees

  • Ph.D. Cardiovascular Physiology, Colorado State University 
  • M.S. Cardiovascular Physiology, Colorado State University
  • B.S.E. Exercise Science, University of Dayton

Professional Activities

  • American Physiological Society, Member
  • The Physiological Society, Member
  • American College of Sports Medicine, Member 

Research Interests

Integrative cardiovascular control in humans focused on:

  • the interaction between sympathetic neural vasoconstrictor and local metabolic factors in the regulation of muscle blood flow and vascular tone,
  • specific vasodilating pathways (e.g. nitric oxide, prostaglandins, and vascular hyperpolarization) involved in the regulation of vascular tone.

Selected Publications

  • Crecelius A.R., G.J. Luckasen, D.G. Larson and F.A. Dinenno. (In Press). KIR channel activation contributes to onset and steady-state exercise hyperemia in humans. Am J Physiol Heart Circ Physiol. 
  • Crecelius, A.R., B.S. Kirby and F.A. Dinenno. (In Press). Intravascular ATP and the regulation of blood flow and oxygen delivery in humans". Exercise and Sport Science Reviews. 
  • Crecelius, A.R., and F.A. Dinenno. (2014). Understanding ATP-mediated vasodilatation in humans: our hyper-polarizing story. Physiology News. (94):38-44.
  • Crecelius A.R., J.C. Richards, G.J. Luckasen, D.G. Larson and F.A. Dinenno. (2013). Reactive hyperemia occurs via activation of inwardly-rectifying potassium channels and Na+/K+-ATPase in humans. Circ Res. 113(8):1023-32. DOI:10.1161/CIRCRESAHA.113.113.01675
  • Crecelius A.R., B.S. Kirby, G.J. Luckasen, D.G. Larson and F.A. Dinenno. (2013). Mechanisms of rapid vasodilatation following a brief contraction in human skeletal muscle.  Am J Physiol Heart Circ Physiol. 305(1):H29-40. DOI:10.1152/ajpheart.00298.2013. 
  • Crecelius A.R., B.S. Kirby, J.C. Richards, and F.A. Dinenno. (2013). Mechanical effects of muscle contraction increase intravascular ATP in humans.  J Appl Physiol. 114:1085-93. Read article >>
  • Kirby B.S., A.R. Crecelius, J.C. Richards, and F.A. Dinenno. (2013). Sources of intravascular ATP during exercise in man: critical role for skeletal muscle perfusion.  Exp Physiol.  98:988-98.  
  • Crecelius A.R., B.S. Kirby, G.J. Luckasen, D.G. Larson and F.A. Dinenno. (2012). ATP-mediated vasodilatation occurs via activation of inwardly-rectifying potassium channels in humans. J Physiol. 590:5349-5359. 
  • Kirby B.S., A.R. Crecelius, W.F. Voyles, and F.A. Dinenno. (2012). Impaired skeletal muscle blood flow control with advancing age in humans: attenuated ATP release and local vasodilation during erythrocyte deoxygenation.  Circ Res. 111:220-230.
  • Richards, J.C., A.R. Crecelius, B.S. Kirby, D.G. Larson and F.A. Dinenno. (2012). Muscle contraction duration and fibre recruitment influence blood flow and VO2 independent of contractile work during steady-state exercise in humans.  Exp Physiol. 97:750-761.
  • Richards J.C., A.R. Crecelius, and B.S. Kirby. (2011). Muscle afferent feedback during exercise: putting the pressure on flow. J Physiol. 589:5923-5924.
  • Crecelius A.R., B.S. Kirby, J.C. Richards, L.J. Garcia, W.F. Voyles, D.G. Larson, G.J. Luckasen and F.A. Dinenno. (2011). Mechanisms of ATP-mediated vasodilation in humans: modest role for nitric oxide and prostaglandins.  Am J Physiol Heart Circ Physiol. 301:H1302-H1310.
  • Crecelius A.R., B.S. Kirby, W.F. Voyles, and F.A. Dinenno. (2011). Augmented skeletal muscle hyperaemia during hypoxic exercise in humans is blunted by combined inhibition of nitric oxide and vasodilating prostaglandins.  J Physiol. 589:3671-3683. 
  • Kirby B.S., A.R. Crecelius, W.F. Voyles, and F.A. Dinenno. (2011). Modulation of postjunctional  α-adrenergic vasoconstriction during exercise and exogenous ATP infusions in ageing humans.  J Physiol. 589:2641-2653. 
  • Markwald R.R., B.S. Kirby, A.R. Crecelius, R.E. Carlson, W.F. Voyles, and F.A. Dinenno. (2011). Combined inhibition of nitric oxide and vasodilating prostaglandins abolishes forearm vasodilatation to systemic hypoxia in healthy humans.  J Physiol. 589:1979-1990. 
  • Crecelius A.R., B.S. Kirby, W. F. Voyles, and F.A. Dinenno. (2010). Nitric oxide but not vasodilating prostaglandins contributes to the improvement of exercise hyperemia via ascorbic acid in healthy older adults.  Am J Physiol Heart Circ Physiol.  299:H1633-H1641. 
  • Kirby B.S., A.R. Crecelius, W.F. Voyles, and F.A. Dinenno. (2010). Vasodilatory responsiveness to adenosine triphosphate in ageing humans.  J Physiol. 588:4017-4027.
  • Crecelius A.R., P.M. Vanderburgh, and L.L. Laubach. (2008). Contributions of body fat and effort in the 5K run: age and body weight handicap.  J Strength and Cond Res.  22(5):1475-80.

Media Expertise